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Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets - up&up™ - 2 of 4Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets - up&up™ - 3 of 4Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets - up&up™ - 4 of 4
Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets - up&up™ - 1 of 4

Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets Twin Pack - 1000ct - up&up™

$14.29 ($0.01/count)

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At a glance

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • 200mg ibuprofen (NSAID) tablets help relieve pain and control fever
  • Safety cap is designed to help deter unintended ingestion
  • 24ct bottle makes sure you're always prepared for aches and pains

Description

Make sure you're always stocked with a medicine cabinet must-have when you add Ibuprofen Pain Relief & Fever Reducer Tablets from up&up™ to your shopping list. From fevers and accidental bumps to headaches and back pain, these ibuprofen tablets are a versatile solution you'll be happy to have on hand the next time life throws you a curveball.

We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Active Ingredient Strength Value: 200 milligrams
Product Warning: Contains ibuprofen
Product Form: Tablet
Primary Active Ingredient: Ibuprofen
Package Quantity: 1
TCIN: 78656141
UPC: 349483601886
Item Number (DPCI): 094-01-0356
Origin: Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

ibuprofen 200 mg (nsaid)* *nonsteroidal anti-inflammatory drug' '200.0mg

Purpose

Pain reliever/Fever reducer

Uses

temporarily relieves minor aches and pains due to: o backache headache o menstrual cramps o minor pain of arthritis o muscular aches the common cold toothache a temporarily reduces fever

Directions

do not take more than directed the smallest effective dose should be used adults and children 12 years and over: take 1 tablet every 4 to 6 hours while symptoms persist if pain or fever does not respond to 1 tablet, 2 tablets may be used do not exceed 6 tablets in 24 hours, unless directed by a doctor children under 12 years: ask a doctor

Other information

store at 20-25°C (68-77°F), read all warnings and directions before use

Inactive ingredients

colloidal silicon dioxide, croscarmellose sodium, iron oxide red, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, pregelatinized starch, talc, titanium dioxide,,

Shipping details

Estimated ship dimensions: 2.71 inches length x 4.59 inches width x 4.94 inches height
Estimated ship weight: 0.82 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: The bottles used to be labeled gluten free...now they are not? The website still states they are but why take it off?? This has always been my go to for this reason, as many companies do not label it. Is it not safe for us anymore?

submitted by Akelly - 5 years ago

  • A: it's actually not on the carton or the bottle i just bought of this. She is correct it is not on all.

    submitted byjen - 4 years ago

  • A: Hi Akelly - Thank you for your questions about the gluten status of the product. You also wanted to know why the gluten status is no longer printed on the product and if it is still safe to take by people that can’t have gluten. The answer to your questions is: The product is gluten free. The “gluten free” status is printed on the both the product carton and product bottle. I hope this information helps. Happy shopping - Keacia

    submitted byKeacia - 5 years ago
    Target staff support

  • A: why is this no longer labeled gluten free?

    submitted byN - 3 years ago

  • A: Hello Target Support - need accurate info. Is this GF? The label is no longer on the packaging.

    submitted byJB - 3 years ago

  • A: This product is not at all labeled gluten free on the bottle or the packaging.

    submitted bys - 2 years ago

Q: Is this gluten-free? One of the ingredients is Pregelatinized Starch which may or may not be gluten-free.

submitted by Emily - 3 years ago

  • A: Confirmed product is gluten free 10/18/2025.

    submitted byCeliacx4 - 9 months ago

  • A: Why is it not labeled Gluten Free? There is no label on the bottle indicating GF.

    submitted byJB - 3 years ago

  • A: Hello - Yes, this item is Gluten-free. Thank you for your question!

    submitted byLorin - 3 years ago
    Target staff support

Q: How large are the bottles for 100 pills

submitted by Sarah - 1 month ago

  • A: Hi, thank you for your question. Please give us a call at 800-719-9260 and reference case number 2166592 with a lot number in order for us to provide you with accurate information.

    submitted bythe Supplier - 1 month ago
    Brand expert

Q: It looks like the same question has been asked multiple times, but this product used to be labeled gluten-free on the bottle and the box, but it is no longer there. So I wanted to ask to confirm nothing changed, and it is still gluten-free?

submitted by Amy - 1 year ago

  • A: Hi Amy - Thank you for reaching out. We appreciate your interest in Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets. It has active ingredient of ibuprofen which is gluten free and has Inactive ingredients of colloidal silicon dioxide, corn starch, croscarmellose sodium, hypromellose, iron oxide red, iron oxide yellow, microcrystalline cellulose, polyethylene glycol, polysorbate 80, stearic acid, titanium dioxide. All these ingredients are Gluten free too. I hope this helps - Emma

    submitted byEmma - 1 year ago
    Target staff support

Q: Are there any animal-derived ingredients in these tablets?

submitted by Target Customer - 6 years ago

  • A: Hi, thank you for your question about the Up&Up Ibuprofen Pain Reliever & Fever Reducer tablets. This product has stearic acid in the inactive ingredients that is derived from animals. If you would like additional information, please let us know and we would be happy to further assist you.

    submitted bythe Supplier - 6 years ago
    Brand expert

  • A: Hi Target Customer – Thanks for viewing our pain relievers! It’s good to always be prepared for aches and pains. I’m going to direct you to the drug facts that is located right below the picture. Thanks for dropping by. - Anita

    submitted byAnita - 6 years ago
    Target staff support

Q: Does it contain Red dye

submitted by Spartan - 2 months ago

  • A: Hi, thank you for your question. The Up & Up Ibuprofen Pain Reliever & Pain Reducer tablets do not contain red dye.

    submitted bythe Supplier - 2 months ago
    Brand expert

Q: Hi! Should this product have a plastic seal around the cap, or does it only come with the foil seal under the cap to determine any potential tampering?

submitted by JW - 8 months ago

  • A: Hi, Thank you for your interest in our Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets - up&up™. It comes with a printed seal under the cap. Hope this helps! - Lima

    submitted byLima - 8 months ago
    Target staff support

Q: Does this product contain any ingredients derived from soy?

submitted by TE - 9 months ago

  • A: Hello, thank you for your question. The product does not contain soy.

    submitted bythe Supplier - 9 months ago
    Brand expert

Q: Where is this product manufactured???? It’s not on the label.

submitted by Mom buyer - 9 months ago

  • A: Hello, thank you for your question. The product is manufactured in the United States. It is required to be listed on the label if made outside of the United States.

    submitted bythe Supplier - 9 months ago
    Brand expert

Q: Do these contain any ingredients derived from dairy? Or are they dairy free?

submitted by AS - 10 months ago

  • A: Hello, thank you for your question. The product does not contain dairy/milk derived ingredients.

    submitted bythe Supplier - 10 months ago
    Brand expert
See all questions (25)

Additional product information and recommendations

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Guests are saying

This ibuprofen product is highly regarded for its effectiveness in relieving pain, including headaches, body aches, and inflammation. Guests appreciate its affordability compared to name brands, with many noting the ease of swallowing the small tablets. The large quantity in each bottle makes it a staple in many households. While some mention a slight odd scent, the overall consensus is that it performs just as well as more expensive alternatives, making it a smart choice for pain relief.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.8 out of 5 stars with 4510 reviews
    quality: 4.66 out of 5
    value: 4.77 out of 5
    91% would recommend
    306 recommendations
    2 out of 5 stars
    24 June, 2026Verified purchase

    (no review title)

    I’ve bought two new bottles in the past few months, and they both smell strongly of plastic. Not the container—the pills themselves. Didn’t used to be like this.
    1 reply from the Product Manufacturer team - 11 days ago
    We are sorry to hear about your experience with the Up & Up Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2174201. We look forward to addressing your concerns and hearing from you!
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    21 June, 2026

    Unsafe, tampered with

    I ordered one as part of my curbside order. Was delivered an open unsealed bottle with missing tablets. I am afraid to take any of them
    1 reply from the Product Manufacturer team - 16 days ago
    We are sorry to hear about your experience with the Up & Up Ibuprofen Pain Reliever & Fever Reducer. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2172830. We look forward to addressing your concerns and hearing from you!
    quality: 1 out of 5
    value: 1 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    20 June, 2026Verified purchase

    Same as Advil/Motrin in EVERY way Except Price!

    There is one, single difference between this Target brand and Advil and Motrin brands -- This significantly cost less than the name brands. They are also safety-coated so they cut down on issues for those prone to heartburn and GERD. It would just be silly to spend $3+ per 100 count bottle to get the named brand.
    Bea
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    6 June, 2026Verified purchase

    Great value and price

    Great value and price. Works just as good as the name brand. Very effective and lasts long.
    ChristyL0401
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    24 May, 2026Verified purchase

    good

    it works
    Princess
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    2 May, 2026

    Don't cut yourself!

    I just cut my thumb horribly on the foil safety seal. I don’t think I have ever cut myself on a safety seal before. Be careful when you open this product!
    1 reply from the Product Manufacturer team - 2 months ago
    We are sorry to hear about your experience with the Ibuprofen (NSAID) Pain Reliever & Fever Reducer Tablets product. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-719-9260 or via email by going to www.perrigo.com/contact-us and reference case number 2157171. We look forward to addressing your concerns and hearing from you!
    Dehn
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    28 March, 2026

    Bye bye muscle aches

    Great for inflammation
    Sarah D
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    23 March, 2026Verified purchase

    ooooooh that smell..

    as much as I take ibuprofen, I noticed these have a strange scent to them 🙄 kinda odd.
    Tiffith
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    19 February, 2026Verified purchase

    (no review title)

    Takes headaches away
    Carlee
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    2 out of 5 stars
    Thumbs down graphic, would not recommend
    16 February, 2026

    Hard no

    I just bought this brand a couple of days ago. WARNING on the bottle there is absolutely no mention of dosage. There are however lots of warnings as would be expected.
    1 reply from the Product Manufacturer team - 5 months ago
    We are sorry to hear about your experience with the Up & Up Ibuprofen. The dosage information should be listed on the bottle, this may be listed under the peel back portion. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2132525. We look forward to addressing your concerns and hearing from you!
    Ann
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    9 February, 2026Verified purchase

    Multi tasker

    These are good for arthritis and bone pain.
    DLRoe
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    7 February, 2026Verified purchase

    Pain relief

    These are just as good as name brand. Easy tablet to swallow and effective for pain.
    Amber
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    4 February, 2026Verified purchase

    (no review title)

    Great value! I’ll keep buying from target.
    Iris666
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    30 January, 2026Verified purchase

    Perfect

    It does exactly what is supposed to do. I swear by up and up products!
    Lindsay
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    11 January, 2026Verified purchase

    Works great!

    Why pay double for name brand when you can get the same results for half the price? I get a lot of headaches and neck pain and this ibuprofen gives me relief every time
    Amanda
    1 guest found this review helpful. Did you?
    3 out of 5 stars
    Thumbs up graphic, would recommend
    8 January, 2026Verified purchase

    (no review title)

    Does the job but they have a weird taste and smell, like Nail glue or smelling chemical ish
    1 reply from the Product Manufacturer team - 6 months ago
    We are sorry to hear about your experience with Up & Up Ibuprofen. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2118853. We look forward to addressing your concerns and hearing from you!
    Meg27
    quality: 3 out of 5
    value: 4 out of 5
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs down graphic, would not recommend
    3 January, 2026

    (no review title)

    Quick & easy delivery. Thank you very much.
    betty
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    27 December, 2025Verified purchase

    (no review title)

    this works as well as the name brand for half the price
    Liz S
    quality: 5 out of 5
    value: 5 out of 5
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    25 October, 2025Verified purchase

    Works well

    Really great price! It’s cheaper to buy two of these than the single pack of 200.
    Andi
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    4 October, 2025Verified purchase

    Just as Good as Name Brand

    This works just as good as the name brand ibuprofen and for a fraction of the price.
    Christopher
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?

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