Fluticasone Propionate Allergy Relief Nasal Spray - 72 sprays/0.38 fl oz - up&up™
Only at target
$9.89 ($26.03/fluid ounce)
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Guests are saying
This allergy nasal spray offers effective relief comparable to name brands like Flonase, making it a great choice for guests seeking affordable allergy management. With a four-pack option, it provides convenience for families dealing with seasonal allergies. Many guests appreciate its ease of use and the absence of drowsiness, while some note minor issues with the pump design. Overall, it stands out as a reliable and budget-friendly alternative for allergy sufferers.
Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
4.7 out of 5 stars with 2402 reviews
effectiveness: 4.53 out of 5
quality: 4.55 out of 5
value: 4.41 out of 5
83% would recommend
110 recommendations
1 out of 5 stars
Thumbs down graphic, would not recommend
22 June, 2026Verified purchase
Nose bleeds.
This is the one that dries your nose.. to the point it bleeds. Target’s blue box is just as good but has silicone to aid moisture inside nose.
1 reply from the Product Manufacturer team - 16 days ago
We are sorry to hear about your experience with the Fluticasone Propionate Allergy Relief Nasal Spray We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact our Contact Center Team at 1-800-719-9260 or via email by going to www.perrigo.com/contact-us and reference case number 2172561. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
13 June, 2026Verified purchase
(no review title)
100% customer satisfaction
1 out of 5 stars
Thumbs down graphic, would not recommend
11 June, 2026Verified purchase
Deceptive packaging
The container is so small that it runs out too quickly and doesn't last long enough for the price you paid. You don't get enough sprays, and that's how they rip you off with deceptive packaging.
1 reply from the Product Manufacturer team - 29 days ago
We are sorry to hear about your experience with the Up & Up Fluticasone Propionate Allergy Relief Nasal Spray. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2169119. We look forward to addressing your concerns and hearing from you!
1 out of 5 stars
Thumbs down graphic, would not recommend
7 June, 2026
Stuffed Nose Relief
I can't stand this stuff.its the very worst and very expensive.i like the sprays with the active ingredient of Oxy Hydrochloride in it,it works 99.9%better than this garbage.
1 reply from the Product Manufacturer team - 1 month ago
We are sorry to hear about your experience with Fluticasone Propionate Allergy Relief Nasal Spray - up&up. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2167835. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
23 May, 2026Verified purchase
(no review title)
same as Flonase
5 out of 5 stars
15 April, 2026Verified purchase
(no review title)
This allergy spray works very well on nasal allergies.
5 out of 5 stars
29 March, 2026
Instruction sheet says doctors have prescribed for 20+ years
Excellent instruction sheet. Informative, and easy to read.
5 out of 5 stars
21 March, 2026Verified purchase
Works!
Easy to use works efficiently
5 out of 5 stars
Thumbs up graphic, would recommend
14 March, 2026Verified purchase
allergy helper
helps with breakthrough allergy stuffiness. It is not a total decongestant like Afrin, but does help in addition to allergy meds for mild stuffiness and itchiness. As good as Flonase
5 out of 5 stars
22 February, 2026Verified purchase
Target rocks
Good job Target
5 out of 5 stars
Thumbs up graphic, would recommend
18 January, 2026Verified purchase
Great Value
Great value especially if use regularly or have multiple family members.
5 out of 5 stars
Thumbs up graphic, would recommend
9 October, 2025Verified purchase
Great product!
I have bad allergies, been using this for 10+ years. Keeps me from itching my nose constantly.
1 out of 5 stars
Thumbs down graphic, would not recommend
2 October, 2025
Shameful Price Gauging of Generic Medicine
This store brand generic is overpriced by about 80%. I advise purchasing elsewhere. The savings is too much to overlook
1 out of 5 stars
Thumbs down graphic, would not recommend
30 September, 2025Verified purchase
Misleading
Not even half full!!!!
1 reply from the Product Manufacturer team - 9 months ago
We are sorry to hear about your experience with the Up & Up Nasal Spray. We take customer service concerns very seriously and are committed to providing our customers with high quality products. We strongly encourage you to contact us at 1-800-719-9260 or email by going to www.perrigo.com/contact-us and reference case number 2088187. We look forward to addressing your concerns and hearing from you!
5 out of 5 stars
Thumbs up graphic, would recommend
21 August, 2025
Same As Flonase
Same as Flonase but cheaper. I will continue to purchase.
5 out of 5 stars
Thumbs up graphic, would recommend
3 August, 2025
originally posted on Sozie

Amazing value - an allergy family's must have!
[This review was collected as part of a promotion.] I was thrilled that this four pack was offered! There are three of us in the house who suffer from allergies and name brand products become expensive. My son used this and didn't notice a difference from his other name brand medication. It's easy to open and easy to close, and had the same medication as his other name brand pump at a fraction of the cost. Great purchase! I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
1 August, 2025
originally posted on Sozie

Perfect nasal spray for allergy relief!
[This review was collected as part of a promotion.] I purchased this for my household because we all suffer from seasonal allergies. I typically will use an allergy pill along with a nasal spray. This spray definitely provided relief. It is very easy to use and comparable to a well known name brand product. I love that it comes with 4 bottles so everyone in my family can each have their own. This nasal spray is non drowsy and at full prescription strength! I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
22 July, 2025
originally posted on Sozie

Effective and affordable nasal spray
[This review was collected as part of a promotion.] I’ve been using this product for a couple of years based on when my allergies hit. I really see no difference between this and what a doctor would prescribe. I’ve never questioned. It’s effectiveness and it’s ability to do the job that it’s prescribed to do I did like that. It came in a four pack because it made price more affordable versus just buying one at a time. I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
19 July, 2025
originally posted on Sozie

Have allergies? You need this!
[This review was collected as part of a promotion.] The Up and Up full prescription strength Fluticasone nasal spray is the go to in our family when it’s allergy season in the south, which pretty means year round. We like the 4 pack because it’s a little more inexpensive than buying individual bottles and because we have a big family, this helps. We stopped using the name brand because the up and up version works the same for us. I received an incentive to write this review.
5 out of 5 stars
Thumbs up graphic, would recommend
17 July, 2025
originally posted on Sozie

Allergy Relief Nasal Spray Box of Four
[This review was collected as part of a promotion.] This allergy spray by up&up is an excellent value. It has four bottles in the box and up to 576 sprays. This will last me a really long time. My doctor always recommends doing an allergy nasal spray for my seasonal allergies along with a pill and I think it really does help with my congestion. The bottles are easy to use and the spray is really strong. I would highly recommend this product if you need a nasal spray. I received an incentive to write this review.