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Tylenol 8 Hour Arthritis Pain Reliever Extended-Release Caplets - Acetaminophen - 2 of 4Tylenol 8 Hour Arthritis Pain Reliever Extended-Release Caplets - Acetaminophen - 3 of 4Tylenol 8 Hour Arthritis Pain Reliever Extended-Release Caplets - Acetaminophen - 4 of 4
Tylenol 8 Hour Arthritis Pain Reliever Extended-Release Caplets - Acetaminophen - 1 of 4

Tylenol 8 Hour Arthritis Pain Reliever Extended-Release Caplets - Acetaminophen - 225ct

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$23.49 ($0.10/count)

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At a glance

About this item

Highlights

  • Tylenol 8 Hour Arthritis Pain Caplets with acetaminophen for minor arthritis pain
  • Works quickly to relieve minor arthritis pain that lasts up to 8 hours
  • Also provides fast-acting pain relief of backache, headache & menstrual cramps
  • Each pain relief caplet contains 650 mg of acetaminophen
  • Extended-release, bi-layer caplet design for powerful pain relief
  • Works as a fever reducer & helps alleviate pain symptoms related to the common cold
  • This minor arthritis pain relief medicine can be used by adults 18 years & older
  • Tylenol is the #1 doctor recommended OTC brand for arthritis pain

Description

Tylenol 8 Hour Arthritis Pain Reliever Extended-Release Caplets temporarily relieves the minor aches and pains of arthritis, including minor arthritis pain in hands, wrists, knees, ankles, elbows and feet. The first layer of the bi-layer design delivers fast-acting medicine for quick minor arthritis pain relief while the second has an extended release, offering effective pain relief that lasts up to 8 hours. With 650 milligrams of the pain-relieving and fever reducing ingredient acetaminophen per caplet, this pain medicine also temporarily relieves aches and pains associated with muscular aches, backache, premenstrual and menstrual cramps, the common cold, headache, and toothache. This effective oral pain reliever is gentle on your stomach, but tough on minor arthritis pain and also works as a fever reducer. Made by the #1 doctor recommended OTC brand for pain relief and fever reduction, it can be used by adults 18 years older and is safe when used as directed.
Key Ingredients: Acetaminophen: Pain reliever and fever reducer
How to Use: Do not take more than directed (see overdose warning) Adults: Take 2 caplets every 8 hours with water. Swallow whole; do not crush, chew, split or dissolve. Do not take more than 6 caplets in 24 hours. Do not use for more than 10 days unless directed by a doctor. Under 18 years of age: Ask a doctor.
Brand Story: TYLENOL® – The #1 doctor recommend brand of pain and fever relief – provides families with a variety of OTC pain relief products to relieve discomfort from minor aches and pains.
Suggested Age: 18 Years and Up
Health Facts: Contains Acetaminophen
Active Ingredient Strength Value: 650 Milligrams
Product Warning: Contains Acetaminophen
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 225
TCIN: 47950061
UPC: 300450838377
Item Number (DPCI): 094-01-0949
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

acetaminophen(650mg).

Purpose

Pain Reliever/Fever Reducer..

Uses

minor pain of arthritis, muscular aches, backache, premenstrual and menstrual cramps, the common cold, headache, toothache.

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:: skin reddening,blisters,rash. If a skin reaction occurs, stop use and seek medical help right away.

Do not use

Do not use: with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.,if you are allergic to acetaminophen or any of the inactive ingredients in this product.

Stop use and ask a doctor if

Stop use and ask a doctor if: pain gets worse or lasts more than 10 days,fever gets worse or lasts more than 3 days,new symptoms occur,redness or swelling is present. These could be signs of a serious condition.

Directions

Do not take more than directed (see overdose warning).

Adults

Take 2 caplets every 8 hours with water. Swallow whole; do not crush, chew, split or dissolve. Do not take more than 6 caplets in 24 hours. Do not use for more than 10 days unless directed by a doctor.

Under 18 Years Of Age

Ask a doctor.

Other information

Store between 20-25 degrees C (68-77 degrees F). Do not use if carton is opened. Do not use if foil inner seal imprinted with Tylenol is broken or missing.

Inactive ingredients

carnauba wax, hydroxyethyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, modified starch, povidone, powdered cellulose, pregelatinized starch, sodium starch glycolate, titanium dioxide, triacetin

Question or comments?

877-895-3665

Shipping details

Estimated ship dimensions: 2.6 inches length x 2.91 inches width x 4.94 inches height
Estimated ship weight: 0.25 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.
Download the safety data sheet (PDF)
This document lists product hazards, safety info and any potential ill effects on human health. All info has been collected and verified by the manufacturer.

Q: Are these dye free??

submitted by chaseorchid16 - 3 days ago

  • A: Hello. Yes, this product does contain dye in its ingredients.

    submitted byKenvue - 3 days ago
    Brand expert

Q: what is the difference betwen extra strength Tylenol and 8 hour arthrits tylenol?

submitted by Liz - 2 months ago

  • A: Hello Liz, Both product has the same active ingredients (acetaminophen). Tylenol extra strenght has 500mg, while Tylenol 8 Hour Arthritis caplet has 650mg and a extended-release caplet.They differ in dosage and how long they last.

    submitted byKenvue - 2 months ago
    Brand expert

Q: Must it be taken with food?

submitted by bushrudd - 3 months ago

  • A: Yes, You can take TYLENOL without regard to meals.

    submitted byKenvue - 3 months ago
    Brand expert

Q: Are each caplet 650 mg, so 6 caplets would be 3900 mg of acetaminophen?

submitted by BSM - 10 months ago

  • A: Yes, each Tylenol 8 Hour Arthritis Pain Extended-Release Caplet has 650 mg of acetaminophen. Taking 6 caplets would amount to 3,900 mg of acetaminophen in total. Please remember, the maximum advised daily limit for this medication is 3,900 mg, which corresponds to 6 caplets within a 24-hour timeframe.

    submitted byKenvue - 10 months ago
    Brand expert

Q: Is this product gluten free?

submitted by Eden - 1 year ago

  • A: Not Available – No information about this attribute/ingredient/usage claim can be confirmed.

    submitted byKenvue - 1 year ago
    Brand expert

Q: Can this medicine cause drowsiness or tiredness

submitted by Poster - 2 years ago

  • A: Hello. Thank you for your question. This medicine will not cause drowsiness or tiredness. You can check our website for warning symptoms. We always suggest to ask a health professional before use.

    submitted byKenvue - 2 years ago
    Brand expert

Q: Can I take these while using Eliquis.

submitted by jose - 2 years ago

  • A: For questions regarding the safety of taking different medications together, we recommend reaching out to your primary care provider!

    submitted byKenvue - 2 years ago
    Brand expert

Q: how many do you take

submitted by Noni - 4 years ago

  • A: Adults take 2 caplets every 8 hours with water. Do not take more than 6 caplets in 24 hours or use them for more than 10 days unless directed by a doctor!

    submitted byKenvue - 4 years ago
    Brand expert

Q: how do I add a 2nd idea to my cart

submitted by help - 5 years ago

  • A: Hi there! We recommend reaching out to Target if you're having trouble adding a second item to your cart.

    submitted byKenvue - 5 years ago
    Brand expert

Q: Is this Tylenol 8 hour arthritis Gluten Free?

submitted by Judy - 7 years ago

  • A: Gluten is not part of the Tylenol® Arthritis Pain Extended-Release product manufacturing process. However, we do not currently test our final products for this ingredient and we cannot confirm that the product or any ingredients in the product are free of it. We strongly recommend that you first consult your doctor before using any product if you have any form of Gluten intolerance or sensitivity, since they are most familiar with your medical history.

    submitted byKenvue - 7 years ago
    Brand expert
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Guests are saying

This product is highly regarded for its extended release formula, providing reliable pain relief for up to 8 hours, making it ideal for daily use. Guests appreciate its gentle effect on the stomach and ease of swallowing, which allows them to manage arthritis and joint pain effectively. Many have found it to be a lifesaver, enabling them to maintain an active lifestyle without constant dosing. Overall, it is a trusted choice for consistent comfort.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.7 out of 5 stars with 1292 reviews
    quality: 4.76 out of 5
    value: 4.53 out of 5
    91% would recommend
    49 recommendations
    5 out of 5 stars
    26 June, 2026
    originally posted on influenster.com
    Image

    This is such a lifesaver! The extended-release formula works steadily and reliably — one tablet provides solid relief for a full 8 hours, so I don’t have to keep taking doses all day. It eases stiff joints and deep muscle pain really well, is gentle on my

    This is such a lifesaver! The extended-release formula works steadily and reliably — one tablet provides solid relief for a full 8 hours, so I don’t have to keep taking doses all day. It eases stiff joints and deep muscle pain really well, is gentle on my stomach, and easy to swallow. Perfect for daily use, reliable, and exactly what I need for consistent comfort. Highly recommended!
    DaihanaH
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 June, 2026Verified purchase

    (no review title)

    Great for arthritis
    Julia
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    17 June, 2026Verified purchase

    Arthritis relief

    Helps with my arthritis pain
    caponeb
    quality: 5 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    14 June, 2026Verified purchase

    (no review title)

    I like Tylenol Arthritis Strength a lot. Especially those days when you need an edge off the pain.
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs down graphic, would not recommend
    31 May, 2026

    (no review title)

    always a pleasure... ✅
    Thomas
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    26 April, 2026Verified purchase

    (no review title)

    Easy to take
    Lovwine
    quality: 5 out of 5
    value: 4 out of 5
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    14 March, 2026

    A believer of this product

    I've been using this product for years and very satisfied with the results. But please advise your delivery person not to leave package outside of a ten storage building door. Incompetent person not good for any company.
    Pepper
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    31 January, 2026
    originally posted on influenster.com
    Image

    Long-lasting, gentle pain relief that helps manage

    The extended-release formula provides long-lasting relief without being harsh on my stomach. I like that it works gently but effectively, allowing me to stay active and comfortable. The caplets are easy to take,
    annat632_2151
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    20 November, 2025
    originally posted on tylenol.com
    Image

    I would recommend Tylenol pain relief to anyone!

    [This review was collected as part of a promotion.] I tried Tylenol arthritis pain relief caplets on the advice of our pharmacist after he explained to me about the benefits of this medication. I was having a lot of knee pain. This is definately the product for me. Shortly after taking the 1st two caplets, I felt great relief of my knee pain. Thanks to Tylenol arthritis pain relief!
    Ruthie
    4 guests found this review helpful. Did you?
    4 out of 5 stars
    14 November, 2025
    originally posted on influenster.com
    Image

    Helps with joint pain

    These really seem to help with aching joints. I have tried other OTC for arthritis pain and this seems to work for me the best. Packaging is fine with no problems.
    lindal370_3744
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    14 October, 2025Verified purchase

    pain be gone

    i use these forarthritis pain already
    thomas
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    1 October, 2025Verified purchase

    Don't have anything else to add

    The produ.\nCt is great
    Marilyn
    1 guest found this review helpful. Did you?
    4 out of 5 stars
    30 September, 2025
    originally posted on influenster.com
    Image

    Good pain relief

    This really helps manage my joint pain throughout the day. I don’t have to keep reaching for more pills every few hours, which is a big relief. It’s gentle on my stomach compared to some other pain meds and kicks in fairly quickly. The caplets are a bit large, but manageable with water. Overall, it’s reliable, effective, and makes daily aches a lot easier to handle.
    kobe9_75
    3 guests found this review helpful. Did you?
    4 out of 5 stars
    6 September, 2025
    originally posted on tylenol.com
    Image

    (no review title)

    Why do you not show safe dosage on label ie: how many pills can be safely taken per 24 hrs.
    Taff
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    24 August, 2025
    originally posted on influenster.com
    Image

    Over the counter relief

    This is a great over the counter medicine to help ease the pain in your joints and arthritis. It comes in a box with a bottle inside. When you take 2 tablets it helps relieve your pain up to 8 hrs.
    pamelak33_1297
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    12 August, 2025
    originally posted on influenster.com
    Image

    Good items

    Show a person taking TYLENOL® 8 HR Arthritis Pain in the morning with sunrise in the background. Capture a person peacefully sleeping with a bottle of TYLENOL® 8 HR Arthritis Pain on the nightstand.
    jennifer2799_5967
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    21 June, 2025

    Works great for overnight

    My mom and brother love this for arthritis pain at night and told me to get it. I can now sleep through the night without waking up for pain. During the day I take the generic 500 mg tablets because it’s cheaper.
    Carly
    quality: 5 out of 5
    value: 4 out of 5
    3 guests found this review helpful. Did you?
    4 out of 5 stars
    1 June, 2025
    originally posted on influenster.com
    Image

    Helps

    I'm an artist and I use my hands a lot to create knitted, woven, sculpted, painted, and/or drawn items. Though I do not have arthritis, thankfully, my hands still ache sometimes. This helps on those days.
    baddercadaver_5919
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    18 April, 2025
    originally posted on tylenol.com
    Image

    Easy to swallow and no side effects.

    [This review was collected as part of a promotion.] This Tylenol is the best yet reduces pain very fast with no side effects I give give it a ten.
    Cat ,56
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    16 March, 2025Verified purchase

    My Needed Helper

    Great job with sr. Aches & pains!
    Miss diane
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?

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